GPR75 - Probable G-protein coupled receptor 75

Probable G-protein coupled receptor 75 is a protein that in humans is encoded by the GPR75 gene. GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand. GPR75 is currently classified as an orphan GPCR and several studies are underway to identify its ligand. In one study, the chemokine CCL5 (RANTES) has been shown to stimulate calcium mobilization and inositol triphosphate formation in GPR75-transfected cells. GPR75 is rare mutation gene, leading to only one working copy of it. Being in this rare group of people is associated with a lower body weight and 54 percent lower odds of obesity. These results are consistent across multiple ancestries, environmental exposures and genetic backgrounds, and they strongly suggest GPR75 is one of many genes involved in weight gain.

Gene location in human

Whole exome sequencing, which can help us find mutations in certain genes and therefore reveal their effects. Instead of sequencing each and every gene in the human genome, exome sequencing focuses only on exons, which make up about one percent of all DNA. Exons are the pieces that provide instructions for proteins, which means when you sequence this entire subset you can identify mutations in protein-coding regions of any gene. Such variations are generally quite rare, but when they are found, they "self-identify" causative genes.

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RPA - UiPath

What is RPA? RPA (Robotic Process Automation) is technology which let organization to make their task easy by allowing them to automate the task just like a human being was doing them across application and systems. The purpose of RPA is to transfer the process execution from humans to bots. Robotic process automation interacts with the existing IT architecture with no complex system integration required. UiPath - The vendor UiPath is a New York City-based global software company that develops a platform for robotic process automation (RPA). The company's software monitors user activity to automate repetitive front and back office tasks, including those performed using other business software such as customer relationship management or enterprise resource planning (ERP) software. UiPath develops software to automate repetitive digital tasks normally performed by people. The technology combines emulating how humans read computer screens (AI Computer Vision) with APIs, and give

Some Pseudoscience and myths we still believe

Hi frnd, In this post I have mentioned some science fact and myth, among which some myth are not properly proof by science yet. But we still used to believe in that. That are also known as Pseudoscience. Bad Small Can Make You Sick According to the once-popular miasma theory, diseases were caused by "bad air." Miasma is the name for this foul-smelling, poisonous vapor that carried particles of decaying matter. In 1854, epidemiologists traced a deadly outbreak of cholera to water contamination. Discovering no organic matter in the water that was undoubtedly causing all the cholera, John Snow debunked miasma theory by proving that cholera is a waterborne disease. Soon, germ theory caught on and miasma flew out the window. Diffrent Parts of Tongue Have Different Taste Maybe this is one you learned in school, and maybe even still believe. Sorry, the idea that the tip of your tongue picks up sour tastes, or the middle of your tongue processes sweetness, or whatever, i

Alien could be discovered on this new class of 'Hycean' exoplanet.

In the discovery for Alien life, astronomers have mostly looked for planets of a similar size, mass, temperature, and atmospheric composition to Earth. Recently, the team of astronomers find a class of planets that may prove the existence of Alien Life. Such exoplanets are more numerous in planetary surveys than rocky ones, which means they could be fertile territory in the search for alien life. The researchers have dubbed them 'Hycean' worlds. In the new study, researchers identify one such class of alien worlds "Hycean" planets, which are up to 2.5 times larger than Earth and feature huge oceans of liquid water beneath hydrogen-rich atmospheres. Hycean planets appear to be incredibly abundant throughout the Milky Way galaxy, and they could host microbial life similar to the "extremophiles" that thrive in some of Earth's harshest environments, study team members said. "Hycean planets open a whole new avenue in our search for life elsewhere,"

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