GPR75 - Probable G-protein coupled receptor 75

Probable G-protein coupled receptor 75 is a protein that in humans is encoded by the GPR75 gene. GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand. GPR75 is currently classified as an orphan GPCR and several studies are underway to identify its ligand. In one study, the chemokine CCL5 (RANTES) has been shown to stimulate calcium mobilization and inositol triphosphate formation in GPR75-transfected cells. GPR75 is rare mutation gene, leading to only one working copy of it. Being in this rare group of people is associated with a lower body weight and 54 percent lower odds of obesity. These results are consistent across multiple ancestries, environmental exposures and genetic backgrounds, and they strongly suggest GPR75 is one of many genes involved in weight gain.

Gene location in human

Whole exome sequencing, which can help us find mutations in certain genes and therefore reveal their effects. Instead of sequencing each and every gene in the human genome, exome sequencing focuses only on exons, which make up about one percent of all DNA. Exons are the pieces that provide instructions for proteins, which means when you sequence this entire subset you can identify mutations in protein-coding regions of any gene. Such variations are generally quite rare, but when they are found, they "self-identify" causative genes.

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SCADA Network

So welcome to my blog. In this post I am gonna write about SCADA network. This actually come to my mind because of web show named Mr. Robot. The show is awesome if you love hacking believe me you will enjoy the series. So basically the SCADA ( Supervisory Control and Data Acquisition ) is a control system architecture comprising computers, networked data communications and graphical user interface for high level process supervisory management, while also comprising other peripheral devices like programmable logic controllers and discrete proportional-integral-derivative controllers to interface with process plant or machinery. SCADA networks used for monitoring and controlling the industry like telecommunication, water plant, etc. It is one of the most commonly used industrial control system, in spite of concerns about SCADA system being vulnerable to cyberattack. This network is used for gathering info about the system, transferring that info to central site, alerting...

NVIDIA Tesla V100 - First Tensor Core GPU

8x NVIDIA Tesla V100 32GB Server As we all know NVIDIA processor are so famous now a days. It give a perfect gaming performance and people used it worldwide. The thing is that it is not only use in personal computer but also at data center, where so many super computer are present for providing services. So, NVIDIA Tesla V100 is a first tensor core GPU. It is especially built to focus on AI, High Performance Computing ( HPC ) and graphics. It is powered by NVIDIA Volta Architecture. It comes with configuration 16 and 32GB and have a performance up to 100 CPUs in single GPU. A single server node with V100 GPUs can replace 60 CPUs nodes. DATA CENTER GPUs Image © NVIDIA NVIDIA V100 for NVLINK Performance with NVIDIA GPU Boost for double precision is 7.8 teraflops and single precision is 15.7 teraflops. Deep learning performance boost is 125 teraflops. Interconnect bandwidth with bidirectional is 300 GB/s. It have memory capacity of 32/16 GB HBM2 with bandwidth 900GB/s. I...

The Amazing Vantablack Material...!!

Vantablack is a material developed by Surrey NanoSystems in the United Kingdom and is one of the darkest substances known, absorbing up to 99.96% of visible light (at 663 nm if the light is perpendicular to the material).The name is a compound of the acronym VANTA (vertically aligned carbon nanotube arrays) and the color black. Vantablack is not actually a color pigment or a paint, but a coating of carbon nanotubes. These have the property of absorbing incident light almost completely. Against a deep black background, objects coated in Vantablack material seem to disappear, as the perception of spatial depth is lost. This is because the human eye perceives shapes coated in Vantablack to be two-dimensional. IUPAC Name is Activated carbon high density skeleton. Other names are Multiwalled carbon nanotube (MWCNT), Vantablack S-VIS and Vantablack S-IR. It is insoluble in water. When light strikes Vantablack, instead of bouncing off, it becomes trapped and is continually deflected amo...

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